Durham, NORTH%20CAROLINA10 Active Studies

Multiple Myeloma Clinical Trials in Durham, NORTH%20CAROLINA

Find 10 actively recruiting multiple myeloma clinical trials in Durham, NORTH%20CAROLINA. Connect with local research sites and explore new treatment options.

10
Active Trials
9
Sponsors
1,368
Enrolling

Recruiting Multiple Myeloma Studies in Durham

RecruitingDurham, NORTH%20CAROLINANCT05730036

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

This study is researching an experimental drug called linvoseltamab, also called REGN5458. Linvoseltamab has previously been studied by itself (without other cancer drugs) in participants who had adv...

410 participants
Regeneron Pharmaceuticals
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RecruitingDurham, NORTH%20CAROLINANCT06351631

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bome...

400 participants
Merck Sharp & Dohme LLC
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RecruitingDurham, NORTH%20CAROLINANCT06722235

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Primary immune thrombocytopenia (ITP) is a condition where the immune system mistakenly destroys platelets, which are cells that help stop bleeding. This leads to a low number of platelets, making it ...

171 participants
Takeda
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RecruitingDurham, NORTH%20CAROLINANCT06500884

A Study to Evaluate Preventive Treatments for Talquetamab-related Oral Toxicity

The purpose of this study is to identify preventive treatments that can minimize the occurrence, severity, and duration of talquetamab-related taste changes (dysgeusia), during the prophylaxis (preven...

130 participants
Janssen Research & Development, LLC
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RecruitingDurham, NORTH%20CAROLINANCT05434689

COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide

Similar to the paradigm established in other hematologic malignancies that are considered curable, the achievement of MRD(-) status is necessary for long term disease control in MM. The fact that the ...

80 participants
University of Alabama at Birmingham
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RecruitingDurham, NORTH%20CAROLINANCT05145400

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The stu...

50 participants
UNC Lineberger Comprehensive Cancer Center
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RecruitingDurham, NORTH%20CAROLINANCT06076642

A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases

The main aim of this study is to learn if TAK-881 is safe and well tolerated during long-term use in adults and children with PIDD who are eligible and completed study TAK-881-3001 (NCT05755035). The...

39 participants
Takeda
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RecruitingDurham, NORTH%20CAROLINANCT04925375

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

There is no standard of care therapy for patients with granulomatous-lymphocytic interstitial lung disease (GLILD) seen in common variable immunodeficiency (CVID). Abatacept has recently looked promis...

38 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingDurham, NORTH%20CAROLINANCT04944979

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10)

The purpose of this study is to assess efficacy, safety and pharmacokinetics of Kedrion Immunoglobulin 10% (KIg10) in pediatric patients with Primary Immunodeficiency Disease (PID)....

30 participants
Kedrion S.p.A.
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RecruitingDurham, NORTH%20CAROLINANCT05642455

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

20 participants
Adaptimmune
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About Multiple Myeloma Clinical Trials in Durham

Multiple myeloma is a cancer of plasma cells in the bone marrow that produce abnormal antibodies. It can cause bone damage, kidney problems, and immune deficiency. Treatments have advanced significantly with proteasome inhibitors, immunomodulatory drugs, and CAR-T cell therapy.

There are currently 10 multiple myeloma clinical trials recruiting participants in Durham, NORTH%20CAROLINA. These studies are seeking a combined 1,368 participants. Research is being sponsored by Regeneron Pharmaceuticals, Merck Sharp & Dohme LLC, Takeda and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Myeloma Clinical Trials in Durham — FAQ

Are there multiple myeloma clinical trials in Durham?

Yes, there are 10 multiple myeloma clinical trials currently recruiting in Durham, NORTH%20CAROLINA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What multiple myeloma treatments are being tested?

The 10 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for multiple myeloma.

Data updated March 2, 2026 from ClinicalTrials.gov